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3rd International Symposium on Biology, Prevention, and Treatment of Toxicities After Transplantation and Cellular Therapy


3rd International Symposium on Biology, Prevention, and Treatment of Toxicities After Transplantation and Cellular Therapy Banner

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Add to Calendar 3rd International Symposium on Biology, Prevention, and Treatment of Toxicities After Transplantation and Cellular Therapy 4/28/2023 9:00:00 AM 4/29/2023 1:00:00 PM America/New_York For More Details: https://mskcc.cloud-cme.com/course/courseoverview?EID=36154 Description: This 3rd international Symposium will bring together a diverse group of experts and thought leaders in the fields of HCT, cellular therapies, and related medical subspecialties. Speakers will discuss current advances in the field, mechanisms of toxicities, symptom burden, and late effects after HCT and cellular therapies along with best practices to prevent and treat these complications. This unique ... Zuckerman Research Center, 417 East 68th Street false MM/DD/YYYY


Date & Location
Friday, April 28, 2023, 9:00 AM - Saturday, April 29, 2023, 1:00 PM, Zuckerman Research Center, 417 East 68th Street, New York, NY

Specialties
Specialties - Bone Marrow Transplant, Cellular Therapeutics, Critical Care, Hematology, Immunotherapy, Infectious Diseases, Internal Medicine, Medical Oncology, Solid Tumor Oncology

Overview

This 3rd international Symposium will bring together a diverse group of experts and thought leaders in the fields of HCT, cellular therapies, and related medical subspecialties. Speakers will discuss current advances in the field, mechanisms of toxicities, symptom burden, and late effects after HCT and cellular therapies along with best practices to prevent and treat these complications.

This unique 2-day program will be comprised of sessions dedicated to a wide range of pre-clinical, translational, and clinical topics, including cellular therapies as a model of accelerated aging, CAR T cell-related toxicities, infectious complications, decision science, the role of the gut microbiome in toxicities, debates on how to diagnose and treat difficult complications such as transplant-associated thrombotic microangiopathy, and several keynote lectures from world experts.

Our symposium will help facilitate networking and multidisciplinary research collaborations. Additionally, attendees are invited to a special luncheon (space limited) and a networking/poster reception.

>> Who Should Attend

The target audience for this Symposium includes physicians, advanced practice providers (physician assistants and nurse practitioners), and nurses who treat or refer patients for hematopoietic cell transplantation or immune effector cell therapies (i.e., CAR T cells; tumor infiltrating lymphocytes, or T cell receptor therapy).

In-person or Virtual Registration Available: This Symposium will be available in-person at Memorial Sloan Kettering's Zuckerman Research Center in New York or virtually via Zoom. In-person attendees have the option to register to attend the special luncheon session as well as the networking/poster reception.

>> Special Luncheon Debate (In-person Only)

Available to in-person attendees only, the focus of this optional luncheon session is on Improving Outcomes with Active Acute Leukemia Undergoing Transplant  — Do We Need to Reinduce Patients With Active AML?

Due to space, the luncheon is only available to 50 attendees and selection must be made during course registration. We do recommend early registration in order to secure your spot. Luncheon confirmation will be sent prior to the start of the Symposium.

>> Networking and Poster Reception (In-person Only)

In-person attendees are also invited to attend the networking reception, which will include poster presentations. This event will be held in the lobby of Zuckerman Research Center and RSVP is required. If you are interested in joining the reception, please be sure to select this as an option in your registration. Hors d'oeuvre and refreshments will be served.

>> Call for Abstracts (Submission Deadline: April 7)

We are pleased to invite the submission of abstracts for this Symposium. Abstracts will be selected on the basis of their scientific merit and content quality. Abstract submission is open to all, and we also highly encourage fellows, residents, pharmacists, and advanced practice providers to submit relevant abstracts in the area of biology, prevention, and treatment of toxicities after transplantation and cellular therapy. In addition, abstracts related to trials and/or clinical research in progress will be accepted.

The top five awarded abstracts will receive complimentary registration to the symposium. Abstracts can be submitted through the 'Abstract' tab above. Please do not register prior to receiving confirmation of acceptance.

  • The submission deadline for abstracts is April 7, 2023.
  • Notification of acceptance will be sent April 14, 2023.

Objectives
  1. Identify the mechanisms of the most common treatment-related toxicities after HCT and cellular therapy.
  2. Discuss the best practices in the prevention and treatment of toxicities and symptom burden after HCT and cellular therapy.
  3. Collaborate with a multidisciplinary group of colleagues to discuss, brainstorm, and plan future quality improvement and research efforts to reduce toxicities, improve the patient experience, and decrease non-relapse mortality.

Registration

Registration Fees (In-person and Virtual)

  • Physicians (MDs, PhDs, PharmDs, and DOs): $450
  • Advanced Practice Providers: $350
  • Residents, Fellows, Nurses, Data Managers, and Other Healthcare Providers: $275
  • MSK Employees: Complimentary
  • Industry Professionals*: $775

*Industry professionals may attend MSK CME activities for their own education. Marketing, sales, and promotion of products and services is strictly prohibited at MSK CME activities. For more information, please visit our Help page.

A registration discount is available for MSK Alumni and MSK Cancer Alliance members to attend this Symposium. If you are a member of one of these groups, contact [email protected] for details. Please note that after your payment has been processed, no further promotional discounts or adjustments will be made to your registration.

In-person Registration

Course registration includes continental breakfast, lunch, refreshment breaks, and an invitation to the Networking and Poster Reception on Friday evening. Please contact [email protected] at least one week prior to the course if you have any special dietary requests or require any specific accommodations.

While MSK requests that institutional guests are vaccinated against COVID-19, we are no longer requiring proof of vaccination. Additional details, including our current Health and Safety Protocols, can be accessed on our Visiting Us page. If you are not feeling well or exhibiting any symptoms of COVID-19, please refrain from attending an in-person event at MSK and contact [email protected] as soon as possible.

Virtual Registration

The virtual option of this program will be delivered through Zoom. Access details, including a link to Zoom and faculty disclosures, will be emailed to virtual registrants prior to the start of the Symposium.

Cancellation Policy

If you wish to cancel your participation in this course, you must email [email protected] at least seven (7) days prior to the start of the course, and your refund will be subject to a $25 administrative fee if attending virtually or a $100 administrative fee if attending in-person. Cancellations or no-shows within seven (7) days of the course are not eligible for a refund. Please note that if it has been more than 120 days since payment was processed, a W9 form must be submitted in order process your refund and your refund will be issued in the form of a check payment. Refunds are not subject to tax. You may substitute another registrant in your place at any time by contacting [email protected] with the appropriate information.

MSK CME reserves the right to cancel or postpone any course due to unforeseen circumstances. In the unlikely event we must cancel or postpone this course, you will be notified via email from MSK CME ([email protected]). A full refund will be issued for your registration. MSK CME is not responsible for any related costs, charges, or expenses to participants, including fees incurred by airline/travel/lodging agencies.


Accreditation

Memorial Sloan Kettering Cancer Center is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

AMA Credit Designation Statement

Memorial Sloan Kettering Cancer Center designates this live activity for a maximum of 14.00 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.



Keywords: AMA PRA Category 1



MSK Symposium Director


Sergio A. Giralt, MD
Deputy Division Head; Attending, Division of Hematologic Malignancies
Melvin Berlin Family Chair in Multiple Myeloma
Chief Medical Officer, MSK Direct
Bone Marrow Transplant and Cellular Therapy Services 
Department of Medicine  

 

MSK Symposium Co-Director


Michael Scordo, MD
Assistant Attending
Bone Marrow Transplant and Cellular Therapy Services 
Department of Medicine  


Symposium Planning Committee

Rafael F. Duarte, MD, PhD, FRCP
Head, Department of Hematology and Transplantation Programme, 
Hospital Universitario Puerta de Hierro Majadahonda;
Profesor Asociado de Hematología - Universidad Autónoma de Madrid
Madrid, Spain

Shahinaz Gadalla, MD, PhD
Senior Investigator, Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics 
National Cancer Institute, NIH
Bethesda, MD 

Vincent T. Ho, MD 
Clinical Director, Adult Hematopoeitic Stem Cell Transplantation 
Dana-Farber Cancer Institute
Boston, MA

Shernan Holtan, MD
Associate Professor of Medicine 
University of Minnesota 
Minneapolis, MN

Robert R. Jenq, MD
Associate Professor, Deputy Chair, Genomic Medicine
University of Texas MD Anderson Cancer Center 
Houston, TX

Karthik Nath, MBBS, PhD
Assistant Attending , Cellular Therapy Service
Memorial Sloan Kettering Cancer Center 
New York, NY 

Armin Rashidi, MD, PhD
Associate Professor
Fred Hutchinson Cancer Center 
Seattle, WA

Gabriela Rondon, MD
Professor, Department of Stem Cell Transplantation - Research, Division of Cancer Medicine
University of Texas MD Anderson Cancer Center 
Houston, TX

Melody Smith, MD, MS
Assistant Professor, Medicine 
Division of Blood and Marrow Transplantation and Cellular Therapy 
Stanford Medicine 
Stanford, CA

Anthony D. Sung, MD
Associate Professor of Medicine
Duke Blood Cancer Center 
Durham, NC

Anna Sureda, MD, PhD
Head of Department, Clinical Hematology Department
Institut Català d’Oncologia - Hospitalet
Barcelona, Spain

Sumithira Vasu, MBBS, MD
Associate Professor
OSU James Cancer Hospital 
Columbus, OH

 

John Reid Wingard, MD 
Deputy Director, University of Florida Health Cancer Center
Director, Bone Marrow Transplant Program 
UF Health Cancer Center 
Gainesville, FL

William A. Wood, MD, MPH
Professor of Medicine
University of North Carolina School of Medicine 
Chapel Hill, NC

Gregory A. Yanik, MD
Professor, Pediatric Hematology/Oncology, Pediatrics, and Internal Medicine,
Medical Director, Bone Marrow, Medical School
University of Michigan Medicine 
Ann Arbor, MI

 

MSK Symposium Faculty 

Genovefa Papanicolaou, MD
Attending Physician
Infectious Disease Service 
Professor, Weill Cornell Medicine

Jonathan Peled, MD, PhD
Assistant Attending
Bone Marrow Transplant and Cellular Therapy Service

Jacob Glass, MD, PhD
Assistant Attending
Leukemia Service

Gunjan L. Shah, MD, MS
Assistant Attending
Bone Marrow Transplant and Cellular Therapy Service

 

Invited Symposium Faculty 

Lawrence A. David, MD, PhD  
Associate Professor, Molecular Genetics and Microbiology 
Duke University School of Medicine
Durham, NC 

Mette Hazenberg, MD, PhD
Cinical Hematologist; Physician-Scientist; Group Leader, Immunologist
Amsterdam UMC and Sanquin Research
Amsterdam, The Netherlands 

Josh Hill, MD
Associate Professor, Vaccine and Infectious Disease and Clinical Research 
Fred Hutchinson Cancer Center
Seattle, WA

Shernan Holtan, MD
Associate Professor of Medicine 
University of Minnesota
Minneapolis, MN 

Jonathan Huggins, MD
Assistant Professor, Medicine and Infectious Diseases 
Duke University School of Medicine
Durham, NC

Nandita Khera, MD, MPH
Professor, Medicine
Mayo Clinic Alix School of Medicine 
Phoenix, AZ

Marcela Maus, MD
Associate Professor, Medicine
Harvard Medical School 
Massachusetts General Hospital Cancer Center
Boston, MA

Laura Niedernhofer, MD, PhD
Director, Institute on the Biology of Aging and Metabolism
The University of Minnesota
Minneapolis, MN

Amanda Olson, MD
Associate Professor
Department of Stem Cell Tranplantation and Cellular Therapy
MD Anderson Cancer Center
Houston, TX

Samir Parekh, MD
Professor of Medicine
Mount Sinai
New York, NY

Daniel Richardson, MD
Assistant Professor
The University of North Carolina
School of Medicine
Chapel Hill, NC 

Mary Mansour Riwes, DO
Assistant Professor
Department of Internal Medicine
Division of Hematology and Oncology 
University of Michigan, Rogel Cancer Center
Ann Arbor, MI

Prof. Johannes Schetelig, MD, MSc
Head DKMS Clinical Trials Unit
Head Stem Cell Transplantation Unit
University Hospital Carl Gustav Carus
Technical University Dresden 
Dresden, Germany

Nirali N. Shah, MD, MHSc
Head, Hematologic Malignancies Section
National Cancer Institute, NIH 
Bethesda, MD

Noha Sharafeldin, MD, MSc, PhD
Assistant Professor
Division of Hematology & Oncology 
Institute for Cancer Outcomes and Survivorship 
The University of Alabama at Birmingham
Birmingham, AL

Robert Soiffer, MD
Chief, Division of Hematologic Malignancies 
Dana-Farber Cancer Institute
Boston, MA

Marion Subklewe, MD
Attending Physician
Head of Immunotherapy in Hematology
LMU University Hospital Munich
Munich, Germany



Mitigation of Relevant Financial Relationships


Memorial Sloan Kettering Cancer Center adheres to the ACCME’s Standards for Integrity and Independence in Accredited Continuing Education. Any individuals in a position to control the content of a CE activity, including faculty, planners, reviewers, or others are required to disclose all financial relationships with ineligible companies (commercial interests). All relevant financial relationships have been mitigated prior to the commencement of the activity.



Member Information
Role in activity
Nature of Relationship(s) / Name of Ineligible Company(s)
Michael Scordo, MD
MSK
Activity Co-Director, Faculty
Consulting Fee-Omeros Corporation|Grant or research support-Omeros Corporation|Grant or research support-Amgen, Inc. (Relationship has ended)|Consulting Fee-Kite - A Gilead Company (Relationship has ended)|Grant or research support-Angiocrine Bioscience, Inc.|Consulting Fee-Angiocrine Bioscience, Inc. (Relationship has ended)
Faculty Photos
Sergio Giralt, MD
MSK
Activity Director, Faculty
Consulting Fee-AMGEN|Grant or research support-Bristol-Myers Squibb|Consulting Fee-GlaxoSmithKline|Consulting Fee-Bristol-Myers Squibb|Consulting Fee-Johnson and Johnson|Consulting Fee-jazz|Consulting Fee-sanofi|Consulting Fee-KITE|Consulting Fee-Novartis AG
Jacob Glass, MD, PhD
MSK
Conflict of Interest Peer Reviewer, Faculty
Nothing to disclose
Karthik D Nath, MBBS
MSK
Conflict of Interest Peer Reviewer, Faculty, Planner
Nothing to disclose
Lawrence David, MD, PhD
Duke University Schoool of Medicine
Faculty
Nothing to disclose
Mette D. Hazenberg, MD, PhD
Amsterdam UMC and Sanquin Research
Netherlands
Faculty
Nothing to disclose
Josh Hill, MD
Fred Hutchinson Cancer Center
Faculty
Consulting Fee-Octapharma AG (Relationship has ended)|Consulting Fee-OptumHealth (Relationship has ended)|Consulting Fee-Karius|Consulting Fee-Pfizer, Inc.|Consulting Fee-Covance/CSL Behring|Consulting Fee-Up-to-Date|Consulting Fee-Century Therapeutics|Consulting Fee-Takeda Pharmaceuticals, Inc.|Consulting Fee-Eversana|Consulting Fee-Gilead (Relationship has ended)|Consulting Fee-Allovir|Consulting Fee-SymBio|Consulting Fee-SentiBio|Advisor-Moderna|Advisor-Allovir|Grant or research support-Allovir|Grant or research support-Gilead (Relationship has ended)|Advisor-Karius|Grant or research support-Takeda Pharmaceuticals, Inc.|Grant or research support-Merck and Company, Inc.|Grant or research support-Oxford Immunotec|Grant or research support-Deverra
Jonathan Huggins, MD, MD, MSCE
Duke University Schoool of Medicine
Faculty
Nothing to disclose
Nandita Khera, MD, MPH
Mayo Clinic
Faculty
Consulting Fee-Incyte Corporation (Relationship has ended)
Marcela Maus, MD, PhD
Massachusetts General Hospital Cancer Center
Faculty
Consulting Fee-Adaptimmune, Agenus, Allogene, Arcellx, Astellas, AstraZeneca, Atara, Bayer, BMS, Cabaletta Bio (SAB), Cellectis (SAB), CRISPR therapeutics, EMD Serono, Genocea, In8bio (SAB), Intellia, GSK, Kite Pharma, Micromedicine/BendBio, Neximmune, Novartis, Oncternal, Sanofi, Synthekine, TCR2 (SAB), Tmunity, and Werewolf, WindMIL (SAB)|Royalties or Patent Beneficiary-Marcela V. Maus, MD., PhD, is an inventor on patents related to adoptive cell therapies, held by Massachusetts General Hospital and University of Pennsylvania (some licensed to Novartis). MVM holds equity in TCR2, Century Therapeutics, Genocea, Oncternal, and Neximmune, and has served as a consultant for multiple companies involved in cell therapies. (Relationship has ended)|Grant or research support-Kite Pharma, Servier, Novartis (Relationship has ended)|Stocks or stock options, excluding diversified mutual funds-Century Therapeutics, Genocea, Oncternal, TCR2, 2Seventy Bio (Relationship has ended)|Board of Directors Member-2SeventyBio
Laura J Niedernhofer, MD, PhD, Director
The University of Minnesota
Faculty
Grant or research support-Pfizer, Inc.|Grant or research support-Merck and Company, Inc.
Amanda Olson, MD
The University of Texas MD Anderson Cancer Center
Faculty
Nothing to disclose
Genovefa Papanicolaou, MD
MSK
Usa
Faculty
Honoraria-shionogi|Honoraria-advarra|Advisor-Cidara|Honoraria-Merck and Company, Inc.|Advisor-Behring|Consulting Fee-AlloVIr|Consulting Fee-Octapharma|Consulting Fee-Symbio|Independent Contractor (included contracted research)-Merck and Company, Inc. (Relationship has ended)|Advisor-Takeda Pharmaceuticals, Inc.|Advisor-Astellas
Samir Parekh, MD
Mount Sinai
Faculty
Nothing to disclose
Jonathan (Tsoni) U Peled, MD, PhD
MSK
Faculty
Other: Research Funding, Intellectual Property Fees, Travel Reimbursement-Seres Therapeutics|Consulting Fee-DaVolterra|Advisor-Postbiotics+ Research LLC
Daniel Richardson, MD
The University of North Carolina | School of Medicine
Faculty
Nothing to disclose
Mary Riwes, DO
Faculty
Nothing to disclose
Johannes Schetelig, MD, M.Sc.
University Hospital Carl Gustav Carus; Technical University Dresden
Faculty
Advisor-Abbvie (Relationship has ended)|Advisor-Johnson and Johnson|Advisor-Bristol-Myers Squibb (Relationship has ended)|Advisor-AstraZeneca (Relationship has ended)|Advisor-BG Medicine (Relationship has ended)
Nirali Shah, MD, MHSc
National Cancer Institute, NIH
Faculty
Nothing to disclose
Gunjan Shah , MD, MS
MSK
Faculty
Grant or research support-Johnson and Johnson|Grant or research support-Amgen|Grant or research support-Beyond Spring|Grant or research support-Bristol-Myers Squibb|Review Panel Member-Arcellx
Noha Sharafeldin, MD PhD
The University of Alabama at Birmingham
Faculty
Nothing to disclose
Robert Soiffer, MD
Dana-Farber Cancer Institute
Faculty
Consulting Fee-Astella|Consulting Fee-Vor Biopharma|Consulting Fee-Smart Immune|Consulting Fee-Neovii|Consulting Fee-Bluesphere Bio|Consulting Fee-Cugene|Consulting Fee-Jasper|Advisor-Celgene
Marion Sabine Subklewe, MD, internist with focus on hematology
LMU University Hospital Munich
Germany
Faculty
Grant or research support-Amgen, BMS/Celgene, Gilead, Janssen, Miltenyi, Morphosys, Novartis, Roche, Seagen, Takeda|Speakers Bureau-Amgen, AstraZeneca, BMS/Celgene, Gilead, GSK, Miltenyi, Novartis, Pfizer, Roche, Takeda|Advisor-LMU Klinikum Med III
Rafael Duarte, MD
Hospital Universitario Puerta de Hierro Majadahonda
Faculty, Planner
Honoraria-Gilead|Honoraria-Merck and Company, Inc.|Honoraria-Takeda Pharmaceuticals, Inc.
Shahinaz Gadalla, MD, PhD
National Cancer Institute, NIH
Faculty, Planner
Nothing to disclose
Vincent Ho, MD
Dana-Farber Cancer Institute
Faculty, Planner
Consulting Fee-Omeros|Advisor-Alexion|Grant or research support-Jazz|Grant or research support-CareDx|Review Panel Member-Allovir|Advisor-Orca-Bio
Shernan G Holtan, MD
The University of Minnesota
Faculty, Planner
Grant or research support-Incyte Corporation|Grant or research support-Vitrac Therapeutics|Review Panel Member-CSL Behring
Robert Jenq, MD
The University of Texas MD Anderson Cancer Center
Faculty, Planner
Advisor-Seres|Advisor-Kaleido (Relationship has ended)|Advisor-LISCure (Relationship has ended)|Advisor-MaaT Pharma|Advisor-Prolacta
Armin Rashidi, MD, PhD
Fred Hutchinson Cancer Center
Faculty, Planner
Consulting Fee-Seres Therapeutics
Gabriela Rondon, MD
The University of Texas MD Anderson Cancer Center
Faculty, Planner
Consulting Fee-Omeros Pharma Corporation
Melody Smith, MD, PhD
Stanford Medicine
Faculty, Planner
Advisor-Bristol-Myers Squibb (Relationship has ended)
Anthony Sung, MD
Duke Blood Cancer Center
Faculty, Planner
Consulting Fee-Targazyme|Grant or research support-Clasado|Grant or research support-DSM/iHealth|Grant or research support-Merck and Company, Inc.
Anna Sureda, MD
Institut Català d'Oncologia - Hospitalet
Faculty, Planner
Consulting Fee-Takeda Pharmaceuticals, Inc.|Advisor-Sanofi-Aventis|Honoraria|Honoraria-Sanofi-Aventis|Honoraria-Gilead|Consulting Fee-Gilead|Grant or research support-Takeda Pharmaceuticals, Inc.|Consulting Fee-Johnson and Johnson|Advisor-Novartis AG|Honoraria-Novartis AG|Honoraria-Takeda Pharmaceuticals, Inc.|Honoraria-Bristol-Myers Squibb|Consulting Fee-Bristol-Myers Squibb
Sumithira Vasu, MBBS
OSU James Cancer Hospital
Faculty, Planner
Advisor-Omeros Inc|Grant or research support-Sanofi
John Reid R. Wingard, MD
UF Health Cancer Center
Faculty, Planner
Consulting Fee-Celgene|Consulting Fee-Merck and Company, Inc.|Consulting Fee-Takeda Pharmaceuticals, Inc.|Other: Consulting Fee-Cidara|Consulting Fee-Orca|Consulting Fee-Ansun
William Wood, MD, MPH
The University of North Carolina | School of Medicine
Faculty, Planner
Advisor-Koneksa Health|Paid consultant-Teladoc|Advisor-Quantum Health|Grant or research support-Genentech, Inc.|Grant or research support-Pfizer, Inc. (Relationship has ended)
Gregory Yanik, MD
The Univesity of Michigan Medicine
Faculty, Planner
Grant or research support-Jazz Pharmaceuticals (Relationship has ended)|Honoraria-Sanofi-Aventis (Relationship has ended)

Friday, April 28, 2023
SYLLABUS DISCLAIMER
8:00AM - 8:05AM

Please note only the presentations from faculty that have given their consent will be available below:

 


Relevant Financial Relationships
8:05AM - 8:10AM

To view faculty disclosures, please visit the course website (mskcc.org/toxicities) and select the Faculty tab. All relevant financial relationships have been mitigated prior to the commencement of the activity.


Transplant as a Model of Accelerated Aging
9:00AM - 10:00AM
Laura J Niedernhofer, MD, PhD, Director
Immune Aging and Senolytics
10:00AM - 10:15AM
Shernan G Holtan, MD
Cognitive Impacts of Accelerated Aging in BMT
10:15AM - 10:30AM
Noha Sharafeldin, MD PhD
Biomarkers of Aging in BMT and Next Steps in Our Field
10:30AM - 10:45AM
Shahinaz Gadalla, MD, PhD
Cellular Therapies as a Model of Accelerated Aging Panel Discussion Q&A
10:45AM - 11:00AM
Blocking IFN– Enhancement of CAR T cell Proliferation Without Increasing CRS
11:20AM - 11:45AM
Marcela Maus, MD, PhD
A New, but Familiar Foe: IEC-HS (HLH)
11:45AM - 12:00PM
Nirali Shah, MD, MHSc
Parkinsonian Neurotoxicity After BCMA CAR T cells
12:00PM - 12:15PM
Samir Parekh, MD
CAR-HEMATOTOX: Prolonged Cytopenias After CAR T cell Therapy
12:15PM - 12:30PM
Marion Sabine Subklewe, MD, internist with focus on hematology
Post CAR T Cell Infections
12:30PM - 12:45PM
Jonathan Huggins, MD, MD, MSCE
CAR T Toxicities Panel Discussion Q&A
12:45PM - 1:00PM
Special Luncheon Debate
1:30PM - 2:00PM
Sergio Giralt, MD
Johannes Schetelig, MD, M.Sc.
CMV in the Lung: Pathogen, Paradigm, Puzzle
3:00PM - 3:15PM
Genovefa Papanicolaou, MD
Respiratory Viral Infections: Acute and Persistent Lung Effects
3:15PM - 3:30PM
John Reid R. Wingard, MD
Viral Specific T Cell Therapy for Polyomavirus: Overcoming BK and JC Virus After Cell Therapy
3:30PM - 3:45PM
Amanda Olson, MD
HHV-6 Reactivation and Related Complications After HCT and CAR-T cell Therapies
3:45PM - 4:00PM
Josh Hill, MD
Infections as Toxicities Panel Discussions Q&A
4:00PM - 4:15PM
Adoption or De-adoption of Evidence Into Practice in Transplantation and Cellular Therapy
5:00PM - 5:15PM
Nandita Khera, MD, MPH
Remote Performance Status Monitoring Using Wearables and PROs
5:15PM - 5:30PM
Jacob Glass, MD, PhD
Incorporating Patient Reported Outcomes Into Standard of Care Practice
5:30PM - 5:45PM
Gunjan Shah , MD, MS
Integrating Patient Values and Preferences Into Treatment Decision Making
5:45PM - 6:00PM
Daniel Richardson, MD
Decision Science and Toxicities Panel Discussion Q&A
6:00PM - 6:15PM
 
Abstracts

Biopsy proven kidney specific-thrombotic microangiopathy without systemic markers of hemolysis in patients with chronic kidney disease after allogeneic hematopoietic cell transplantation
9:00AM - 9:10AM

Khanh Doan BA1, Jennifer Saultz DO1, Brandon Hayes-Lattin MD1, Robert Rope MD2, Jessica Weiss MD2, Nicole Andeen MD3, Jessica Leonard MD1, Levanto Schachter DO1, Yazan Migdady MD1, Rachel Cook MD1, Richard T. Maziarz MD1, Laura Newell MD1, Gabrielle Meyers MD1, Arpita Gandhi MD1. 1Center for Hematologic Malignancies Division of Hematology & Oncology, 2Oregon Health and Science University. Division of Nephrology and Hypertension, 3Department of Pathology, Oregon Health & Science University, Portland, OR


CAR T-Associated Infection: A Single-Center, Five-Year Retrospective
9:10AM - 9:20AM

Cosmo Fowler, MD1, Kate Tayban, ACNP-BC1, Elena Mead, MD1 1Memorial Sloan Kettering Cancer Center, Anesthesiology & Critical Care Medicine


Connected Care Remote Monitoring after Discharge from Inpatient Autologous or Allogeneic Stem Cell Transplant
9:20AM - 9:30AM

Robert Daly, Jessie Holland, Jennifer Cracchiolo, Camila Bernal, Jill Ackerman, Morgan Moy, Stephanie Benardis, Lilly Reilly, Holly Wallace, Pam Hill, Esperanza Papadopoulos, Michael Scordo, Gunjan L. Shah


Deposition of complement components C5b-9 and MASP2 in tissues is not a feature of GVHD and may assist in discriminating GVHD from thrombotic microangiopathy following allogenic transplantation
9:30AM - 9:40AM

Mohammad Alhomoud1, Cynthia Magro2, Alexandra Gomez-Arteaga1, Nora Chokr1, Samuel Yamshon1, Adrienne Phillips1, Sebastian Mayer1, Tsiporah Shore1, Jeffrey Laurence1 1Division of Hematology and Oncology, Department of Medicine, Weill Cornell Medicine/New York Presbyterian Hospital, New York, NY, USA 2Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA


Dermatologic adverse events associated with chimeric antigen receptor T-cell therapy: a pharmacovigilance analysis of the FDA reporting system
9:40AM - 9:50AM

Ryan Storgard MS, Stephen Dusza DrPH, Miguel Perales MD, Roni Shouval MD PhD, Michael Scordo MD, Alina Markova MD


Encouraging Outcomes after Second Hematopoietic Cell Transplants with Unrelated Cord Blood Grafts for Post-Transplant Relapse in Pediatric Patients
9:50AM - 10:00AM

Alexandre G. Troullioud Lucas, MD, MSc1,2, Jaap Jan Boelens, MD, PhD3, Nancy A. Kernan, MD3, Susan E. Prockop, MD4, Kevin J. Curran, MD3, Anne Archer, MSW3, Eric Davis, MPH5, Dorine Bresters, MD2,6, PhD, Wouter Kollen, MD, PhD2,6, Birgitta Versluys, MD, PhD2,6, Marc Bierings, MD, PhD2,6, Caroline A. Lindemans, MD, PhD*2,6, Andromachi Scaradavou, MD*3 *These authors have contributed equally to this work (1)MSK Kids, Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, (2)Hematopoietic Cell Transplantation, Princess Maxima Center for Pediatric Oncology, Utrecht, Netherlands, (3)MSK Kids, Transplantation and Cellular Therapy, Memorial Sloan Kettering Cancer Center, New York, NY, (4)Pediatrics, Boston Children’s Hospital, Boston, MA, (5)Department of Medicine, Adult Bone Marrow Transplant Service, Memorial Sloan Kettering Cancer Center, New York, NY, (6)Department of Pediatrics, University Medical Center Utrecht, UU, Utrecht, Netherlands


Free interleukin-18 is elevated in CD22 CAR T-cell associated hemophagocytic lymphohistiocytosis-like toxicities
10:00AM - 10:10AM

Joseph M. Rocco1, Jon Inglefield2, Bonnie Yates3, Daniel A. Lichtenstein4, Yanyu Wang2, Laurence Goffin5, Djordje Filipovic5, Eduardo J. Schiffrin5, Nirali N. Shah3 1Laboratory of Immunoregulation, NIAID, NIH, Bethesda, USA. 2Pediatric Oncology Branch, Center for Cancer Research, NCI, NIH, Bethesda, USA. 3Applied Developmental Research Directorate, Leidos Biomedical Research, Frederick, USA. 4University of Cincinnati, Department of Internal Medicine, Cincinnati, USA. 5AB2Bio, EPFL Innovation Park, Lausanne, Switzerland.


Intrathecal Hydrocortisone for Treatment of Children and Young Adults with CAR T-cell Immune-Effector Cell Associated Neurotoxicity Syndrome
10:10AM - 10:20AM

Haneen Shalabi, DO1, Cynthia Harrison1, Bonnie Yates, MSN, PNP1, Katherine R. Calvo, MD, PhD2, Daniel W. Lee, MD3, and Nirali N. Shah, MD, MHSc1, 1Pediatric Oncology Branch, National Cancer Institute, Bethesda, MD, 2Hematology Section, Department of Laboratory Medicine, Clinical Center, National Institutes of Health, Bethesda MD; 3Department of Pediatric Hematology/Oncology, Department of Pediatrics, University of Virginia, Charlottesville, VA


Successful incorporation of electronic patient reported outcomes using PROMIS-29 into standard of care after hematopoietic stem cell transplant and chimeric antigen receptor T cell therapy.
10:20AM - 10:30AM
Saturday, April 29, 2023
Updates on the Diagnosis and Treatment of TA-TMA: Discussion with Experts
8:00AM - 9:00AM
Rafael Duarte, MD
Anna Sureda, MD
Vincent Ho, MD
Sumithira Vasu, MBBS
Sergio Giralt, MD
Pulmonary Toxicities of Cellular Therapies
9:00AM - 9:30AM
Gregory Yanik, MD
Nutrition and Microbiota in Allo-HCT
9:45AM - 10:00AM
Jonathan (Tsoni) U Peled, MD, PhD
FMT for Treatment of Acute GVHD
10:00AM - 10:15AM
Mette D. Hazenberg, MD, PhD
FMT as Prophylactic Supportive Care
10:15AM - 10:30AM
Armin Rashidi, MD, PhD
Plant Sequencing and Gut Microbiome in Allo-HCT
10:30AM - 10:45AM
Lawrence David, MD, PhD
Nutritional Interventional Trial to Improve the Mircrobiome and Prevent Acute GVHD
10:45AM - 11:00AM
Mary Riwes, DO
Nutrition – Microbiome and Toxicities Panel Discussion Q&A
11:00AM - 11:15AM
Harmonization of Toxicity Definitions – Challenges – Process and Example
11:45AM - 12:45PM
Robert Soiffer, MD

Memorial Sloan Kettering gratefully acknowledges the following organizations for providing educational grants for this live activity:

Actinium Pharmaceuticals, Inc.
Angiocrine Bioscience, Inc.
Jazz Pharmaceuticals, Inc.
Novartis
Omeros Corporation


Memorial Sloan Kettering gratefully acknowledges the following organizations for providing financial support and co-sponsoring this live activity:

American Society for Transplantation and Cellular Therapy


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