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The Robert Steel Symposium in Developmental Oncology


The Robert Steel Symposium in Developmental Oncology Banner

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Add to Calendar The Robert Steel Symposium in Developmental Oncology 5/2/2022 8:30:00 AM 5/3/2022 2:00:00 PM America/New_York For More Details: https://mskcc.cloud-cme.com/course/courseoverview?EID=30160 Description: Registration is closed for the symposium and we will not be taking onsite registration. Dr. Alex Kentsis welcomes you to The Robert Steel Symposium in Developmental Oncology. The Tow Center for Developmental Oncology unites scientists across MSK to develop fundamental insights into the molecular mechanisms of cancers in children and young adults, and to devise new approaches for definitive therap... Zuckerman Research Center, 417 East 68th Street false MM/DD/YYYY


Date & Location
Monday, May 2, 2022, 8:30 AM - Tuesday, May 3, 2022, 2:00 PM, Zuckerman Research Center, 417 East 68th Street

Specialties
Specialties - Bone Marrow Transplant, Breast Medical Oncology, Cellular Therapeutics, Computational Biology, Epidemiology, Gastrointestinal Oncology, Genetics, Genitourinary Oncology, Gynecologic Oncology, Head and Neck Oncology, Hematology, Immigrant Health and Cancer Disparities, Immunotherapy, Internal Medicine, Laboratory Medicine, Leukemia, Lymphoma, Medical Oncology, Molecular Biology, Neuro-Oncology, Neurosurgery, Oncology and Hematology, Orthopedic Surgery, Pediatrics, Radiation Oncology, Solid Tumor Oncology, Surgical Oncology, Thoracic Medical Oncology

Overview

Registration is closed for the symposium and we will not be taking onsite registration.

Dr. Alex Kentsis welcomes you to The Robert Steel Symposium in Developmental Oncology.

The Tow Center for Developmental Oncology unites scientists across MSK to develop fundamental insights into the molecular mechanisms of cancers in children and young adults, and to devise new approaches for definitive therapy and control.

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The Robert Steel Symposium in Developmental Oncology will bring together outstanding scientists from across the country to discuss the latest discoveries into the molecular mechanisms of cancers in children and young adults and the development of new approaches for their definitive therapy and control. The symposium is the first of its kind which is dedicated to new science at the interface of human development and cancer pathogenesis. This program will feature interactive discussions of fundamental and translational research to address unanswered questions in the field of developmental oncology.

There are many unanswered questions that need to be addressed for childhood and young adult cancers:

  • What causes cancer in children and young adults without inheritance of cancer-predisposing mutations or exposure to environmental mutagens? How do predisposing alleles and exposures contribute to cancer development?
  • What developmental processes are dysregulated to cause mutations and cell transformation in otherwise healthy tissues?
  • How do mutations in developmental pathways involving transcription factors and epigenetic signaling cause cancer?
  • How do we design effective therapeutics to block, activate, and modulate protein interactions that control transcription factors and other developmental regulators?
  • How do we identify targets for immune therapy in developmental tumors that have relatively few mutations?

This two-day live in-person symposium will provide an intimate and exciting setting to share new advances for these questions. It will also allow an opportunity for established and young investigators to discuss new questions and interdisciplinary approaches of relevance to young-onset cancer biology.

Who Should Attend

The target audience for this symposium includes scientists, physicians, APPs, nurses, and other healthcare providers interested in learning the latest advances in our understanding of the biology and therapy of childhood cancers. We are pleased to invite students and trainees to attend this symposium on a complimentary basis (please see details below).

We are pleased to offer symposium attendees a special discounted rate at two hotels in the vicinity of Memorial Sloan Kettering. Please select the 'Hotel' tab above for details. 

Safety Precautions Due to COVID-19

The MSK CME team is closely monitoring the impact of COVID-19 on our ability to host in-person events. We thank you for your cooperation as we work together to meet the challenges posed by COVID-19. All registrants will be notified if there are any changes. Your health and safety, and that of our patients and employees, is our highest priority.

Please note that we do hope to host a reception/dinner for attendees on Monday, May 2, pending COVID-19 restrictions. If you are interested in attending a possible reception/dinner, please let us know during registration so we can plan accordingly.

Objectives
  1. Explain biologic and developmental causes of childhood cancers.
  2. Review recently developed therapies for patients with childhood and young-onset cancers.
  3. Discuss new biologic questions in order to accelerate the development of definitive therapies for patients.

Registration

In-Person Registration Fees*

  • All Healthcare Providers: $25
  • Industry Professionals: $45**
  • Students and Trainees: complimentary; please see details below***

*In-person Attendance Requirements: All in-person attendees at MSK CME events must be fully vaccinated against COVID-19 at least two (2) weeks prior to the event. A copy of your COVID-19 vaccination card(s) must be uploaded during registration. All in-person attendees are required to wear masks at all times at all MSK locations (regardless of vaccination status). Please review the current Health & Safety Guidelines for more information.

**Industry professionals may attend MSK CME activities for their own education. Marketing, sales, and promotion of products and services is strictly prohibited at MSK CME activities. For more information, please visit our Help page.

Registration Discounts/Promotions

  • ***We are pleased to invite students and trainees to attend this symposium on a complimentary basis. If you are a student or trainee interested in attending, please email [email protected] for a promotional code (registration is required in order to attend).
  • For students, residents, fellows, and postdocs in need of financial support for travel and hotel, please email [email protected] a request explaining your needs in 250 words or less.
  • A registration discount is available for MSK Alumni and MSK Cancer Alliance to attend a MSK CME course. If you are a member of one of these groups, contact [email protected] for details.
  • Registration is complimentary for all MSK employees; however, you must complete registration through the 'Register' tab above in order to attend this course. If you are registered for this course and are unable to attend, please notify [email protected].

Please note that after your payment has been processed, no further promotional discounts or adjustments will be made to your registration. 

Cancellation Policy

Registration for this symposium is non-refundable. MSK CME reserves the right to cancel or postpone any course due to unforeseen circumstances. In the unlikely event, we must cancel or postpone this course, you will be notified via email from MSK CME ([email protected]). We will refund the registration fee in full but are not responsible for any related costs, charges, or expenses to participants, including fees incurred by airline/travel/lodging agencies. At any time, you may substitute another registrant in your place after contacting MSK CME with the relevant information. Please note that if it has been more than 120 days since payment was processed, a W9 form must be submitted in order to process your refund and your refund will be issued in the form of check payment. Refunds are not subject to tax.

If you are not feeling well or exhibiting any symptoms of COVID-19 please refrain from attending and contact MSK CME ([email protected]).


Accreditation

Memorial Sloan Kettering Cancer Center is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

AMA Credit Designation Statement

Memorial Sloan Kettering Cancer Center designates this live activity for a maximum of 9.00 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

 

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The Robert Steel Foundation for Pediatric Cancer Research was established to honor the memory of Robert Steel, who died in 1984 at the age of eighteen after a heroic two-year struggle against rhabdomyosarcoma. Throughout the years, the Foundation supported MSK programs and initiatives devoted to speeding progress against childhood cancers, and its farsighted generosity has made The Robert Steel Symposium in Developmental Oncology possible. By bringing together leading scientists to address the latest challenges and opportunities in pediatric cancer research and treatment, The Robert Steel Symposium in Developmental Oncology continues to advance the vital work launched by the Robert Steel Foundation for Pediatric Cancer Research more than three decades ago.



Keywords: AMA PRA Category 1

We are pleased to offer symposium attendees a special discounted rate at two hotels in the vicinity of Memorial Sloan Kettering:

Courtyard Marriot, Midtown East
866 3rd Avenue, New York, NY 10022
View website

To receive the MSK discounted rate, please identify yourself as attending a MSKCC event when booking over the phone at +1 (212) 644-1300.

The Kimberly Hotel
145 E 50th Street, New York, NY 10022
View website

Please email [email protected] or call +1 (212) 702-1600 and identify yourself as attending an event at "Memorial Sloan Kettering" to receive the MSK discounted rate on any room.



Course Organizers

Alex Kentsis, MD, PhD
Associate Member
Molecular Pharmacology Program
Director, Tow Center for Developmental Oncology
Memorial Sloan Kettering Cancer Center

Andrew Kung, MD, PhD
Chair, Department of Pediatrics
Memorial Sloan Kettering Cancer Center 

Agata Smogorzewska, MD, PhD
Associate Professor 
The Rockefeller University


Course Speakers 

Sam Behjati, BMBCh, PhD
Group Leader, Wellcome Sanger Institute 
Cambridge University

Ester Calvo Fernández, PharmD
PharmD, PhD Candidate
Columbia University

Jason Chan, MD, PhD
Instructor, Sarcoma Medical Oncology Service - Postdoc, Tammela lab
Memorial Sloan Kettering Cancer Center 

Sisi Chen, PhD
Research Associate
Memorial Sloan Kettering Cancer Center 

Adam Durbin, MD, PhD
Assistant Member
Division of Molecular Oncology
Department of Oncology
St. Jude Children’s Research Hospital

Arielle Elkrief, MD
Research Fellow, Ladanyi Lab
Memorial Sloan Kettering Cancer Center 

Katherine Gadek, PhD
Damon Runyon-Sohn Pediatric Cancer Fellow 
St. Jude Children’s Research Hospital

Liron Grossmann, MD
Hematology-oncology fellow
Children’s Hospital of Philadelphia

Alejandro Gutierrez, MD
Associate Professor of Pediatrics
Boston Children’s Hospital

Luz Jubierre Zapater, PhD
Memorial Sloan Kettering Cancer Center 

Claudia Kleinman, PhD
Assistant Professor
Department of Human Genetics 
McGill University

Coraline Mlynarczyk, PhD
Research Associate in Medicine
Weill Cornell Medicine

Michelle Monje-Deisseroth, MD, PhD
Professor of Neurology and, by Courtesy, of Neurosurgery, of Pediatrics, of Pathology and of Psychiatry and Behavioral Sciences 
Stanford University

Anand Patel, MD, PhD
Instructor
St. Jude Children’s Research Hospital

Maxim Pimkin, MD, PhD
Instructor in Pediatrics, Damon Runyon-Sohn Fellow 
Harvard Medical School

Zulekha Qadeer, PhD
Postdoctoral Scholar
University of California, San Francisco

Miguel Rivera, MD
Associate Professor of Pathology
Massachusetts General Hospital
Harvard Medical School

Charles Roberts, MD, PhD
Director, Comprehensive Cancer Center 
St. Jude Children’s Research Hospital

Kimberly Stegmaier, MD
Co-Director, Pediatric Hematologic Malignancy Program 
Dana-Farber Cancer Institute
Harvard Medical School

Palaniraja Thandapani, PhD
Postdoctoral Fellow
NYU School of Medicine

Andrew Webster, PhD
Rockefeller University

Peng Wu, MD, PhD
Instructor
Stanford University School of Medicine



Mitigation of Relevant Financial Relationships


Memorial Sloan Kettering Cancer Center adheres to the ACCME’s Standards for Integrity and Independence in Accredited Continuing Education. Any individuals in a position to control the content of a CE activity, including faculty, planners, reviewers, or others are required to disclose all financial relationships with ineligible companies (commercial interests). All relevant financial relationships have been mitigated prior to the commencement of the activity.



Member Information
Role in activity
Nature of Relationship(s) / Name of Ineligible Company(s)
Andrew L Kung, MD, PhD
MSK
Activity Co-Director, Faculty
Advisor-Emendo Biotherapeutics|Advisor-Karyopharm Therapeutics|Stocks or stock options, excluding diversified mutual funds-Imago Biosciences|Advisor-DarwinHealth
Agata Smogorzewska, MD, PhD
Rockefeller University
Activity Co-Director, Faculty
Grant or research support-Rocket Pharmaceuticals
Alex Kentsis, MD
MSK
Activity Director, Faculty
Advisor-Novartis AG
Tara O'Donohue, MD, MS
MSK
Conflict of Interest Peer Reviewer
Nothing to disclose
Colleen Maher
MSK
Department Support (manager, assistant, etc)
Nothing to disclose
Sam Behjati, BM, Professor / Consultant
Wellcome Trust Sanger Institute
United Kingdom
Faculty
Nothing to disclose
Ester Calvo Fernández, PharmD
Columbia University
Faculty
Nothing to disclose
Jason E Chan, MD, PhD
MSK
Faculty
Nothing to disclose
Sisi Chen
MSK
Faculty
Nothing to disclose
Adam D Durbin, MD, PhD
St. Jude Children's Research Hospital
Faculty
Consulting Fee-Alphasights, Inc (Relationship has ended)|Consulting Fee-Incrowd, Inc. (Relationship has ended)|Consulting Fee-Putnam Associates (Relationship has ended)
Arielle Elkrief, MD
MSK
Faculty
Nothing to disclose
Katherine Gadek, PhD
St. Jude Children's Research Hospital
Faculty
Nothing to disclose
Liron Grossmann, MD
Children’s Hospital of Philadelphia
Faculty
Nothing to disclose
Alejandro Gutierrez, MD
Boston Children's Hospital
Faculty
Nothing to disclose
Luz Jubierre Zapater
MSK
Faculty
Nothing to disclose
Claudia Kleinman, PhD
McGill University
Faculty
Nothing to disclose
Coraline Mlynarczyk, PhD
Weill Cornell Medicine
Faculty
Nothing to disclose
Michelle Monje-Deisseroth, MD
Stanford Medicine
Faculty
Advisor-Cygnal Therapeutics
Anand Patel, MD, PhD
St. Jude Children's Research Hospital
Faculty
Nothing to disclose
Maxim Pimkin, MD, PhD
DFCI
Faculty
Nothing to disclose
Zulekha Qadeer, PhD
UCSF
Faculty
Nothing to disclose
Miguel Rivera, MD
Massachusetts General Hospital, Harvard Medical School
Faculty
Grant or research support-EMD Serono|Grant or research support-ACD/Biotechne
Charles Roberts, MD, PhD
St. Jude Children's Research Hospital
Faculty
Nothing to disclose
Kimberly Stegmaier, MD, PhD
Dana-Farber Cancer Institute, Harvard Medical School
Faculty
Grant or research support-Novartis AG|Grant or research support-KronosBio|Consulting Fee-KronosBio (Relationship has ended)|Consulting Fee-AstraZeneca (Relationship has ended)|Consulting Fee-Auron Therapeutics (Relationship has ended)|Board of Directors Member-Auron Therapeutics|Honoraria-Bristol-Myers Squibb (Relationship has ended)
Palaniraja Thandapani, PhD
NYU School of Medicine
Faculty
Nothing to disclose
Andrew Webster, PhD
Rockefeller University
Faculty
Nothing to disclose
Peng Wu, MD, PhD
Stanford University School of Medicine
Faculty
Nothing to disclose
Gabriella Casalena, PhD
MSK
Planner
Nothing to disclose

Monday, May 2, 2022
 
On Demand Abstract Posters

SYLLABUS DISCLAIMER
8:30AM - 8:40AM

The online syllabus will not include any of the presentations from the live in-person conference. 
A CD24-directed T cell-engaging bispecific antibody for demoplastic small round cell tumor
8:40AM - 8:50AM
A human pluripotent stem cell derived human in vitro differentiation model for the study of normal and transformed sympatho-adrenal development.
8:50AM - 9:00AM
Centrosomal Vulnerabilities In ZFTA-Rela Ependymoma
9:00AM - 9:10AM
Exploring cell-cell communication networks in medulloblastoma using single-cell genomics
9:10AM - 9:20AM
Towards rational epigenetic combination therapy based on the mechanisms of clinical resistance to EZH2 inhibition in BAF-deficient sarcomas
9:20AM - 9:30AM
Tuesday, May 3, 2022


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