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1st International Symposium on Hematopoietic Cell Transplantation-Related Toxicities


1st International Symposium on Hematopoietic Cell Transplantation-Related Toxicities Banner

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Add to Calendar 1st International Symposium on Hematopoietic Cell Transplantation-Related Toxicities 4/27/2018 7:00:00 AM 4/28/2018 1:00:00 PM America/New_York For More Details: https://mskcc.cloud-cme.com/course/courseoverview?EID=2691 Description: More than 10,000 hematopoietic cell transplantations (HCT) are performed annually in the United States as a potentially curative treatment for over 70 life-threatening illnesses including hematologic cancers, genetic disorders, and other diseases. Despite significant advances in supportive care and improvements in HCT outcomes, 1 in every 3 patients may succumb to HCT-related toxicities, half of which a... Zuckerman Research Center 417 E 68th St false MM/DD/YYYY


Date & Location
Friday, April 27, 2018, 7:00 AM - Saturday, April 28, 2018, 1:00 PM, Zuckerman Research Center 417 E 68th St

Specialties
Specialties - Bone Marrow Transplant, Cardiology, Gastroenterology, Infectious Diseases, Laboratory Medicine, Medical Oncology, Nephrology, Neurology, Oncology and Hematology

Overview

More than 10,000 hematopoietic cell transplantations (HCT) are performed annually in the United States as a potentially curative treatment for over 70 life-threatening illnesses including hematologic cancers, genetic disorders, and other diseases. Despite significant advances in supportive care and improvements in HCT outcomes, 1 in every 3 patients may succumb to HCT-related toxicities, half of which are not related to graft-versus-host disease (GVHD). Following the successful examples of the international symposia focusing on GVHD and relapse after HCT, we are convening the '1st International Symposium on Hematopoietic Cell Transplantation-Related Toxicities.’

This symposium will bring together experts and thought leaders from around the world in the fields of HCT and related medical subspecialties. Speakers will discuss mechanisms of toxicities and symptom burden after HCT in order to identify best practices to both prevent and treat HCT-related toxicities. Over the 2-day symposium, speakers and attendees will also convene in dedicated sessions that will facilitate collaborative efforts in planning future research aimed at mitigating serious toxicities, reducing symptom burden, and improving patients’ outcomes.

Target Audience

The target audience for this symposium includes physicians, researchers, fellows, advanced practice providers, nurses, and pharmacists who provide care for patients undergoing HCT.


Objectives
  1. Discuss the causes and mechanisms of toxicities and symptom burden after HCT in order to identify best practices to prevent and treat them.
  2. Understand the role of vascular endothelial cell damage as a key driver of many toxicities after HCT.

Registration

 Registration Fees   
 Physicians (MDs, PhDs, PharmDs and DOs)  $400
 Residents, Fellows    $200
 NPs, PAs, RNs, and Other Healthcare Providers        $250
 Industry Professionals*  $775

*Industry professionals may attend CME activities for their own education. Marketing, sales, and promotion of products and services is strictly prohibited at MSK CME activities.

Registration includes continental breakfast, lunch, and refreshment breaks. Please contact [email protected] at least one week prior to the course if you have any special dietary needs.

    • 30% Discounted Rate for MSK Alumni and MSK Alliance Members - MSK offers a discounted rate to all MSK Alumni and MSK Alliance members to attend a CME course. Please contact [email protected] for more information or to register.
    • MSK Staff Registration - Registration is complimentary for MSK staff. However, you must complete course registration to attend this course. 

    Cancellation Policy

    If you cancel your participation in this course, your registration fee, less a $75 administrative fee, will be refunded when email notification is received by the MSK Office of Continuing Medical Education (MSK CME) at least 7 days prior to the first day of the course ([email protected]).

    Cancellations or no-shows after this date are not eligible for a refund. MSK CME reserves the right to cancel or postpone any course due to unforeseen circumstances. In the unlikely event we must cancel or postpone this course, we will refund the registration fee in full, but are not responsible for any related costs, charges, or expenses to participants, including fees incurred by airline/travel/lodging agencies. At any time, you may substitute another registrant in your place after contacting MSK CME with the relevant information.


    Accreditation

    Memorial Sloan Kettering Cancer Center is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

    AMA Credit Designation

    Memorial Sloan Kettering Cancer Center designates this live activity for a maximum of 14.00 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.



    Endothelial cells cover image credit: Kandasamy, Biomedical Microscopy Core, Paul D. Coverdell Center



    Keywords:



     

    MSK Course Directors

    Sergio Giralt, MD
    Melvin Berlin Family Chair in Myeloma Research
    Professor of Medicine, Weill Cornell Medicine
    Chief Attending, Adult BMT Service
    Memorial Sloan Kettering Cancer Center

    Miguel-Angel Perales, MD
    Deputy Chief, Adult Bone Marrow Transplantation Service
    Director, Adult Stem Cell Transplantation Fellowship
    Professor of Medicine, Weill Cornell Medicine 
    Associate Member
    Memorial Sloan Kettering Cancer Center

     

    Organizing Committee

    Michelle Donato, MD
    John Theurer Cancer Center - Hackensack Meridian Health 

    Alexander I. Geyer, MD
    Memorial Sloan Kettering Cancer Center

    Tobias M. Hohl, MD, PhD
    Memorial Sloan Kettering Cancer Center

    Edgar A. Jaimes, MD
    Memorial Sloan Kettering Cancer Center

    Markus Y. Mapara, MD, PhD
    NewYork-Presbyterian and Columbia University Medical Center

    Scott D. Rowley, MD
    John Theurer Cancer Center - Hackensack Meridian Health 

    Michael Scordo, MD 
    Memorial Sloan Kettering Cancer Center

    Koen van Besien, MD, PhD
    NewYork-Presbyterian and Weill Cornell Medicine

    William A. Wood, MD, MPH
    UNC Lineberger Comprehensive Cancer Center

     

    MSK Course Faculty

    Dean Carlow, MD, PhD
    Laboratory Medicine

    Edgar A. Jaimes, MD
    Department of Medicine

    Richard N. Kolesnick, MD
    Sloan Kettering Institute

    Genovefa Papanicolaou, MD
    Department of Medicine

    Miguel-Angel Perales, MD
    Department of Medicine

    Bianca D. Santomasso, MD, PhD
    Department of Neurology

    Wendy L. Schaffer, MD, PhD
    Department of Medicine

    Michael Scordo, MD
    Department of Medicine

    Ying Taur, MD, MPH
    Department of Medicine

     

    Invited Faculty

    Minoo Battiwalla, MD
    Sarah Cannon Blood Cancer Network
    Nashville, TN

    Jaap Jan Boelens, MD, PhD
    University Medical Center Utrecht
    Utrecht, Netherlands

    Enric Carreras, MD, PhD
    Josep Carreras Leukaemia Research Institute
    Barcelona, Spain

    Guang-Shing Cheng, MD
    Fred Hutchinson Cancer Research Center
    Seattle, WA

    Kenneth R. Cooke, MD
    Johns Hopkins Sidney Kimmel Cancer Center 
    Baltimore, MD

    Stella M Davies, MBBS, PhD
    Cincinnati Children’s Hospital Medical Center
    Cincinnati, Ohio

    Mary Horowitz, MD
    Chief Scientific Director for the CIBMTR
    Medical College of Wisconsin
    Milwaukee, WI

    Leslie S. Kean, MD, PhD
    Seattle Children’s Hospital
    Seattle, WA

    Thomas Luft, MD, PhD
    Heidelberg University Hospital 
    Heidelberg, Germany

    Markus Y. Mapara, MD, PhD
    NewYork-Presbyterian and Columbia University Medical Center
    New York, NY

    Shahin Rafii, MD, PhD
    NewYork-Presbyterian and Weill Cornell Medicine
    New York, NY

    Gabriela Rondon, MD
    MD Anderson Cancer Center
    Houston, TX

    Michael Satlin, MD, MS
    NewYork-Presbyterian and Weill Cornell Medicine
    New York, NY

    Peter J. Shaw, MD
    The Children’s Hospital at Westmead
    Westmead, Australia 

    Koen van Besien, MD, PhD
    NewYork-Presbyterian and Weill Cornell Medicine
    New York, NY

    William A. Wood, MD, MPH
    UNC Lineberger Comprehensive Cancer Center
    Chapel Hill, NC

     

    Faculty Disclosures (All Faculty)



    Member Information
    Role in activity
    Nature of Relationship(s) / Name of Ineligible Company(s)
    Minoo Battiwalla, MD
    Sarah Cannon Center for Blood Cancer
    Faculty
    Nothing to disclose
    Jaap-Jan Boelens, MD
    MSK
    Faculty
    Nothing to disclose
    Dean Carlow, MD, PhD
    MSK
    Faculty
    Nothing to disclose
    Enric Carreras, MD, PhD
    Josep Carreras International Foundation
    Spain
    Faculty
    Research grant & speakers bureau-Jazz Pharmaceutical
    Guang-Shing Cheng, MD

    Faculty
    Consulting Fee-Gilead
    Kenneth R Cooke, MD
    Johns Hopkins Sidney Kimmel Cancer Center
    Faculty
    Consulting Fee-Jazz Pharmaceuticals|Speakers Bureau-Jazz Pharmaceuticals|support for lab based research-Jazz Pharmaceuticals
    Stella Davies, MBBS, PhD
    Cincinnati Children's Hospital Medical Center
    Faculty
    Consulting Fee-Novartis AG|Consulting Fee
    Faculty Photos
    Sergio Giralt, MD
    MSK
    Faculty
    Consulting Fee-Abbvi|Consulting Fee-Celgene|Consulting Fee-Amgen|Consulting Fee-Sanofi|Consulting Fee-Takeda Pharmaceuticals, Inc.|Consulting Fee-Johnson and Johnson|Consulting Fee-Jazz|Consulting Fee-Novartis AG|Contracted Research-Sanofi-Aventis|Contracted Research-Takeda Pharmaceuticals, Inc.|Contracted Research-Miltenyi|Contracted Research-Sanofi
    Mary Horowitz, MD
    Medical College of Wisconsin
    Faculty
    Unrestricted educational/research support-Bluebird bio|Unrestricted educational/research support-Incyte|Contracted Research-Gilead|Contracted Research-Sanofi-Aventis|Contracted Research-Takeda Pharmaceuticals, Inc.
    Edgar Jaimes, MD
    MSK
    Usa
    Faculty
    Nothing to disclose
    Leslie Kean, MD, PhD
    Faculty
    Consulting Fee-Bristol-Myers Squib Aventis|Consulting Fee-Calimmune|Consulting Fee-Magenta Therapeutics|Contracted Research-Alpine Biosciences|Contracted Research-Regeneron|Consulting Fee-Kymab Ltd|Contracted Research-Bristol-Myers Squibb
    Richard Kolesnick, MD
    MSK
    Faculty
    Founder Ceramedix Holding LLC
    Thomas Luft, PhD
    Heidelberg University Hospital
    Germany
    Faculty
    Contracted Research-JAZZ Pharmaceuticals, Neovii|Speakers Bureau-JAZZ Pharmaceuticals
    Markus Y Mapara, MD
    Columbia University
    Faculty
    Consulting Fee-Incyte|Consulting Fee-Bluebird|Consulting Fee-Janssen|Ownership Interest-Caelum|Scientific Advisor-Caelum|Ownership Interest-CRISPR
    Genovefa Papanicolaou, MD
    MSK
    Usa
    Faculty
    Nothing to disclose
    Miguel Perales, MD
    MSK
    Faculty
    Consulting Fee-Servier|Consulting Fee-Merck and Company, Inc.|Consulting Fee-Incyte|Consulting Fee-Seattle Genetics
    Shahin Rafii, MD

    Faculty
    Nothing to disclose
    Gabriela Rondon, MD
    The University of Texas MD Anderson Cancer Center
    Faculty
    Nothing to disclose
    Bianca D. Santomasso, MD, PhD
    MSK
    Faculty
    Consulting Fee-Juno Therapeutics|Consulting Fee-Kite Pharma
    Michael Satlin, MD, MS
    NewYork-Presbyterian and Weill Cornell Medicine
    Faculty
    Consulting Fee-Achaogen
    Wendy Schaffer, MD
    MSK
    Faculty
    Nothing to disclose
    Michael Scordo, MD
    MSK
    Faculty
    Consulting Fee-Angiocrine Bioscience
    Peter J Shaw, MD
    The Children's Hospital at Westmead
    Australia
    Faculty
    Nothing to disclose
    Ying Taur, MD, MPH
    MSK
    Faculty
    Nothing to disclose
    Koen van Besien, MD
    Weill Cornell Medical Center
    Faculty
    Nothing to disclose
    William Wood, MD, MPH
    The University of North Carolina | School of Medicine
    Faculty
    Nothing to disclose

    Friday, April 27, 2018
     
    Friday

    Disclosure
    7:00AM - 7:01AM
    Registration & Breakfast
    7:00AM - 7:45AM
    Introduction & Welcome
    7:45AM - 8:00AM
    Sergio Giralt, MD
    Video: Introduction & Welcome
    7:45AM - 8:00AM
    Sergio Giralt, MD
    Endothelial Cell Damage as Common Pathway for Toxicity
    8:00AM - 9:00AM
    Shahin Rafii, MD
    Video: Endothelial Cell Damage as Common Pathway for Toxicity
    8:00AM - 9:00AM
    Shahin Rafii, MD
    Idiopathic Pneumonia Syndrome
    9:00AM - 9:20AM
    Kenneth R Cooke, MD
    Video: Idiopathic Pneumonia Syndrome
    9:00AM - 9:20AM
    Kenneth R Cooke, MD
    Sinusoidal Obstruction Syndrome
    9:20AM - 9:40AM
    Enric Carreras, MD, PhD
    Video: Sinusoidal Obstruction Syndrome
    9:20AM - 9:40AM
    Enric Carreras, MD, PhD
    Thrombotic Microangiopathy
    9:40AM - 10:00AM
    Stella Davies, MBBS, PhD
    Video: Thrombotic Microangiopathy
    9:40AM - 10:00AM
    Stella Davies, MBBS, PhD
    Proposed Biomarkers for Endothelial Cell Damage
    10:00AM - 10:30AM
    Thomas Luft, PhD
    Video: Proposed Biomarkers for Endothelial Cell Damage
    10:00AM - 10:30AM
    Thomas Luft, PhD
    Pharmacology of High Dose Therapy
    11:00AM - 11:20AM
    Jaap-Jan Boelens, MD
    Video: Pharmacology of High Dose Therapy
    11:00AM - 11:20AM
    Jaap-Jan Boelens, MD
    Pharmacokinetics of Alkylators
    11:20AM - 11:40AM
    Peter J Shaw, MD
    Video: Pharmacokinetics of Alkylators
    11:20AM - 11:40AM
    Peter J Shaw, MD
    Pharmacokinetic Assays and Methodologies
    11:40AM - 12:00PM
    Dean Carlow, MD, PhD
    Video: Pharmacokinetic Assays and Methodologies
    11:40AM - 12:00PM
    Dean Carlow, MD, PhD
    Mechanisms of Radiation Toxicity
    12:00PM - 12:20PM
    Richard Kolesnick, MD
    Video: Mechanisms of Radiation Toxicity
    12:00PM - 12:20PM
    Richard Kolesnick, MD
    Long Term Survivorship Issues
    1:00PM - 1:45PM
    Minoo Battiwalla, MD
    Video: Long Term Survivorship Issues
    1:00PM - 1:45PM
    Minoo Battiwalla, MD
    Renal Toxicities
    1:45PM - 2:05PM
    Edgar Jaimes, MD
    Video: Renal Toxicities
    1:45PM - 2:05PM
    Edgar Jaimes, MD
    Mucosal Toxicities
    2:05PM - 2:25PM
    Michael Scordo, MD
    Video: Mucosal Toxicities
    2:05PM - 2:25PM
    Michael Scordo, MD
    Cardiovascular Toxicities
    2:25PM - 2:45PM
    Wendy Schaffer, MD
    Video: Cardiovascular Toxicities
    2:25PM - 2:45PM
    Wendy Schaffer, MD
    Pulmonary Toxicities
    2:45PM - 3:05PM
    Guang-Shing Cheng, MD
    Video: Pulmonary Toxicities
    2:45PM - 3:05PM
    Guang-Shing Cheng, MD
    Neurologic Toxicities
    3:05PM - 3:30PM
    Bianca D. Santomasso, MD, PhD
    Video: Neurologic Toxicities
    3:05PM - 3:30PM
    Bianca D. Santomasso, MD, PhD
    Modeling Immune Reconstitution and GVHD After Transplant Using The Tools of Systems Biology
    3:45PM - 4:05PM
    Leslie Kean, MD, PhD
    Video: Modeling Immune Reconstitution and GVHD After Transplant Using The Tools of Systems Biology
    3:45PM - 4:05PM
    Leslie Kean, MD, PhD
    Immune Reconstitution
    4:05PM - 4:25PM
    Miguel Perales, MD
    Video: Immune Reconstitution
    4:05PM - 4:25PM
    Miguel Perales, MD
    Novel Strategies to Reduce CMV Disease in Transplant Patients
    4:25PM - 4:45PM
    Genovefa Papanicolaou, MD
    Video: Novel Strategies to Reduce CMV Disease in Transplant Patients
    4:25PM - 4:45PM
    Genovefa Papanicolaou, MD
    Combating Multidrug-resistant Bacterial Infections During Allogeneic-HCT
    4:45PM - 5:05PM
    Michael Satlin, MD, MS
    Video: Combating Multidrug-resistant Bacterial Infections During Allogeneic-HCT
    4:45PM - 5:05PM
    Michael Satlin, MD, MS
    Harnessing the Microbiome to Improve Transplant Outcomes
    5:05PM - 5:35PM
    Ying Taur, MD, MPH
    Video: Harnessing the Microbiome to Improve Transplant Outcomes
    5:05PM - 5:35PM
    Ying Taur, MD, MPH
    Saturday, April 28, 2018
     
    Saturday

    Disclosure
    8:00AM - 8:01AM
    Next steps
    10:30AM - 11:00AM
    Edgar Jaimes, MD
    Video: Next steps
    10:30AM - 11:00AM
    Edgar Jaimes, MD
    How to Utilize the CIBMTR and BMT CTN to Reduce Toxicities
    11:00AM - 12:00PM
    Mary Horowitz, MD
    Video: How to Utilize the CIBMTR and BMT CTN to Reduce Toxicities
    11:00AM - 12:00PM
    Mary Horowitz, MD

    Memorial Sloan Kettering gratefully acknowledges the following organizations for providing educational grants and financial support for this live activity:

    • Amgen
    • Angiocrine Bioscience, Inc.
    • Jazz Pharmaceuticals, Inc


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